Circulating Nucleic Acids in Serum and Plasma – CNAPS IX

Front Matter....Pages i-xxii
Front Matter....Pages 1-1
Circulating Cell-Free miR-373, miR-200a, miR-200b and miR-200c in Patients with Epithelial Ovarian Cancer....Pages 3-8
Cell-Free miRNA-141 and miRNA-205 as Prostate Cancer Biomarkers....Pages 9-12
Clinical Utility of Circulating Tumor DNA for Molecular Assessment and Precision Medicine in Pancreatic Cancer....Pages 13-17
An Enquiry Concerning the Characteristics of Cell-Free DNA Released by Cultured Cancer Cells....Pages 19-24
Detection of p53 Mutations in Circulating DNA of Transplanted Hepatocellular Carcinoma Patients as a Biomarker of Tumor Recurrence....Pages 25-28
Unbiased Detection of Somatic Copy Number Aberrations in cfDNA of Lung Cancer Cases and High-Risk Controls with Low Coverage Whole Genome Sequencing....Pages 29-32
Liquid Profiling in Lung Cancer – Quantification of Extracellular miRNAs in Bronchial Lavage....Pages 33-37
Screening of KRAS Mutation in Pre- and Post-Surgery Serum of Patients Suffering from Colon Cancer by COLD-PCR HRM....Pages 39-41
Non-dividing Cell Virtosomes Affect In Vitro and In Vivo Tumour Cell Replication....Pages 43-45
Features of Circulating DNA Fragmentation in Blood of Healthy Females and Breast Cancer Patients....Pages 47-51
Liquid Profiling of Circulating Nucleic Acids as a Novel Tool for the Management of Cancer Patients....Pages 53-60
Front Matter....Pages 61-61
Characterization of Human Pregnancy Specific Glycoprotein (PSG) Gene Copy Number Variations in Pre-eclampsia Patients....Pages 63-65
Non-invasive Prenatal Diagnosis of Feto-Maternal Platelet Incompatibility by Cold High Resolution Melting Analysis....Pages 67-70
Implementing Non-Invasive Prenatal Diagnosis (NIPD) in a National Health Service Laboratory; From Dominant to Recessive Disorders....Pages 71-75
Front Matter....Pages 77-77
Comparative Analysis of Harmful Physical Factors Effect on the Cell Genome....Pages 79-84
Heterochromatic Tandem Repeats in the Extracellular DNA....Pages 85-89
A Historical and Evolutionary Perspective on Circulating Nucleic Acids and Extracellular Vesicles: Circulating Nucleic Acids as Homeostatic Genetic Entities....Pages 91-95
Comparison of MicroRNA Content in Plasma and Urine Indicates the Existence of a Transrenal Passage of Selected MicroRNAs....Pages 97-100
A Quantitative Assessment of Cell-Free DNA Utilizing Several Housekeeping Genes: Measurements from Four Different Cell Lines....Pages 101-103
Oligodeoxynucleotide Analogues of Circulating DNA Inhibit dsRNA-Induced Immune Response at the Early Stages of Signal Transduction Cascade in a Cell Type-Dependent Manner....Pages 105-107
Front Matter....Pages 77-77
GC-Rich DNA Fragments and Oxidized Cell-Free DNA Have Different Effects on NF-kB and NRF2 Signaling in MSC....Pages 109-112
Evaluation of the State of Transplanted Liver Health by Monitoring of Organ-Specific Genomic Marker in Circulating DNA from Receptor....Pages 113-116
Vesicular and Extra-Vesicular RNAs of Human Blood Plasma....Pages 117-119
Artificial Analogues of Circulating Box C/D RNAs Induce Strong Innate Immune Response and MicroRNA Activation in Human Adenocarcinoma Cells....Pages 121-125
Multiple Ways of cfDNA Reception and Following ROS Production in Endothelial Cells....Pages 127-131
Protein Content of Circulating Nucleoprotein Complexes....Pages 133-136
Front Matter....Pages 137-137
Digital PCR of Genomic Rearrangements for Monitoring Circulating Tumour DNA....Pages 139-146
mFast-SeqS as a Monitoring and Pre-screening Tool for Tumor-Specific Aneuploidy in Plasma DNA....Pages 147-155
Methodological Variables in the Analysis of Cell-Free DNA....Pages 157-163
Novel Technology for Enrichment of Biomolecules from Cell-Free Body Fluids and Subsequent DNA Sizing....Pages 165-169
A Rapid and Sensitive Method for Detection of the T790M Mutation of EGFR in Plasma DNA....Pages 171-174
Evaluation of Different Blood Collection Tubes and Blood Storage Conditions for the Preservation and Stability of Cell-Free Circulating DNA for the Analysis of the Methylated mSEPT9 Colorectal Cancer Screening Marker....Pages 175-178
Purification of Circulating Cell-Free DNA from Plasma and Urine Using the Automated Large-Volume Extraction on the QIAsymphony® SP Instrument....Pages 179-185
Detection and Quantification of KIT Mutations in ctDNA by Plasma Safe-SeqS....Pages 187-189
Front Matter....Pages 191-191
Lost in Translation? Ethical Challenges of Implementing a New Diagnostic Procedure....Pages 193-197
Front Matter....Pages 199-199
Academia Meets Industry....Pages 201-215
Back Matter....Pages 217-220